| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRAF4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRAF4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9BUZ4 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined, TRAF proteins are associated with, The encoded protein has been shown to interact with neurotrophin receptor, This protein has been found to bind to p47phox, This protein thus, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase, and mediate signal transduction from members of the TNF receptor superfamily, and negatively regulate NTR induced cell death and NF-kappa B activation, is thought to be involved in the oxidative activation of MAPK8/JNK, p75 (NTR/NTSR1), This gene encodes a member of the TNF receptor associated factor (TRAF) family |
| Immunogen: |
A portion of amino acids 427-455 from the human protein was used as the immunogen for this TRAF4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRAF4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRAF4 |
| Short name: |
TRAF4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tumor necrosis factor receptor-associated factor 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CART1 and MLN62 and RNF83, LOC783305 and IDBG-632122 and ENSBTAG00000038990 and 781568, TRAF4 and IDBG-37645 and ENSG00000076604 and 9618, Traf4 and IDBG-202221 and ENSMUSG00000017386 and 22032, WW domain binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005923 and tight junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030323 and respiratory tube development and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050699 and WW domain binding and molecular function this GO :0090073 and positive regulation of protein homodimerization activity and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding and also this GO :0046872 : metal ion binding and also this GO :0050699 : WW domain binding, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, this GO :0046872 : metal ion binding, this GO :0050699 : WW domain binding, 783305, TNF receptor-associated factor 4 |
| Identity: |
12034 |
| Gene: |
TRAF4 |
More about : TRAF4 |
| Long gene name: |
TNF receptor associated factor 4 |
| Synonyms: |
CART1 MLN62 RNF83 |
| Locus: |
17q11, 2 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
X80200 |
| Entrez gene record: |
9618 |
| Pubmed identfication: |
7592751 7490069 |
| RefSeq identity: |
NM_145751 |
| Classification: |
Ring finger proteins TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000132677 |