| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRAF4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRAF4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9BUZ4 |
| Purity: |
Antigen affinity |
| Description: |
It is a member of the TNF receptor associated factor(TRAF) family, Regnier et al, The TRAF4 cDNA, To investigate the biologic function of TRAF4, Tomasetto et al, a family of scaffold proteins, also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF4 gene, was mapped to 17q11-q12 by radioisotopic in situ hybridization, which they designated MLN62, (1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes, (2002) generated Traf4-deficient mice by gene disruption, TNF Receptor-Associated Factor 4 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human TNF Receptor-Associated Factor 4 (PKFISHQDIRKRNYVRDD) was used as the immunogen for this TRAF4 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRAF4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRAF4 |
| Short name: |
TRAF4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tumor necrosis factor receptor-associated factor 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CART1 and MLN62 and RNF83, LOC783305 and IDBG-632122 and ENSBTAG00000038990 and 781568, TRAF4 and IDBG-37645 and ENSG00000076604 and 9618, Traf4 and IDBG-202221 and ENSMUSG00000017386 and 22032, WW domain binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005923 and tight junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030323 and respiratory tube development and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050699 and WW domain binding and molecular function this GO :0090073 and positive regulation of protein homodimerization activity and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding and also this GO :0046872 : metal ion binding and also this GO :0050699 : WW domain binding, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, this GO :0046872 : metal ion binding, this GO :0050699 : WW domain binding, 783305, TNF receptor-associated factor 4 |
| Identity: |
12034 |
| Gene: |
TRAF4 |
More about : TRAF4 |
| Long gene name: |
TNF receptor associated factor 4 |
| Synonyms: |
CART1 MLN62 RNF83 |
| Locus: |
17q11, 2 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
X80200 |
| Entrez gene record: |
9618 |
| Pubmed identfication: |
7592751 7490069 |
| RefSeq identity: |
NM_145751 |
| Classification: |
Ring finger proteins TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000132677 |