| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
E Cadherin (CDH1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the anti-E Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This anti-E Cadherin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P12830 |
| Purity: |
Purified |
| Description: |
E Cadherin is involved in mechanisms regulating cell-cell adhesions, Has a potent invasive suppressor role, It is a ligand for integrin alpha-E/beta-7, They preferentially interact with themselves in a homophilic manner in connecting cells, [UniProt], cadherins may thus contribute to the sorting of heterogeneous cell types, mobility and proliferation of epithelial cells, Cadherins are calcium-dependent cell adhesion proteins |
| Immunogen: |
A portion of amino acids 833-862 from the human protein was used as the immunogen for this anti-E Cadherin antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-E Cadherin antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
E Cadherin (CDH1) |
| Short name: |
E Cadherin Antibody (CDH1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
E-cadherin (epithelial)), classification 1, E Cadherin (Antibody to) (cadherin 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Arc-1 and CD324 and CDHE and ECAD and LCAM and UVO, BT, CDH1 and IDBG-38622 and ENSG00000039068 and 999, Cdh1 and IDBG-190074 and ENSMUSG00000000303 and 12550, DNA-templated and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051260 and protein homooli this GO merization and biological process this GO :0060576 and intestinal epithelial cell development and biological process this GO :0060662 and salivary gland cavitation and biological process this GO :0060693 and regulation of branching involved in salivary gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0071944 and cell periphery and cellular component this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090102 and cochlea development and biological process this GO :2000008 and regulation of protein localization to cell surface and biological process this GO :2001222 and regulation of neuron migration and biological process, E-cadherin (epithelial), Extracellular, cell adhesion molecule binding, this GO :0001701 and in utero embryonic development and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007416 and synapse assembly and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0009636 and response to toxic substance and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010033 and response to organic substance and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016235 and aggresome and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0016342 and catenin complex and cellular component this GO :0019538 and protein metabolic process and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021983 and pituitary gland development and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030054 and cell junction and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030424 and axon and cellular component this GO :0030506 and ankyrin binding and molecular function this GO :0031175 and neuron projection development and biological process this GO :0032794 and GTPase activating protein binding and molecular function this GO :0032880 and regulation of protein localization and biological process this GO :0033268 and node of Ranvier and cellular component this GO :0033561 and regulation of water loss via skin and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042493 and response to drug and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043219 and lateral loop and cellular component this GO :0043220 and Schmidt-Lanterman incisure and cellular component this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043296 and apical junction complex and cellular component this GO :0043679 and axon terminus and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045893 and positive regulation of transcription, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0019903 : protein phosphatase binding and also this GO :0019904 : protein domain specific binding and also this GO :0030506 : ankyrin binding and also this GO :0032794 : GTPase activating protein binding and also this GO :0045295 : gamma-catenin binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0019903 : protein phosphatase binding, this GO :0019904 : protein domain specific binding, this GO :0030506 : ankyrin binding, this GO :0032794 : GTPase activating protein binding, this GO :0045295 : gamma-catenin binding, this GO :0050839 : cell adhesion molecule binding, type 1, 64827 and IDBG-634263 and ENSBTAG00000015991 and 282637, cadherin 1 |
| Identity: |
1748 |
| Gene: |
CDH1 |
More about : CDH1 |
| Long gene name: |
cadherin 1 |
| Synonyms gene: |
UVO |
| Synonyms gene name: |
E-cadherin (epithelial) , cadherin 1, type 1 |
| Synonyms: |
uvomorulin CD324 |
| Synonyms name: |
E-Cadherin |
| Locus: |
16q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
L08599 |
| Entrez gene record: |
999 |
| Pubmed identfication: |
9925936 |
| RefSeq identity: |
NM_004360 |
| Classification: |
Type I classical cadherins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137561 |
| Locus Specific Databases: |
LRG_301 |