| Also known as: |
CDH1 / E Cadherin |
| Other names: |
CAM 120/80, CAM 120/80, CD_antigen: CD324Cleaved into the following 3 chains:E-Cad/CTF1, Cadherin-1, E-Cad/CTF2, E-Cad/CTF3, E-Cadherin, E-cadherin, E-cadherin (epithelial), E-cadherin (epithelial), Epithelial cadherin, Uvomorulin, cadherin 1, cadherin 1, cadherin-1, calcium-dependent adhesion protein, cell-CAM 120/80, epithelial, epithelial cadherin, type 1, uvomorulin, cadherin-1 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CDH1 |
| Other gene names: |
Arc-1, CD324, CDH1, CDHE, CDHE, E-cadherin, ECAD, LCAM, UVO, UVO, CDH1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
3F4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
4 mg/ml |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Proximity Ligation Assay, Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3F4] (IgG1, k) CDH1 / E Cadherin |
| Short name: |
Mouse Monoclonal [clone 3F4] (IgG1, k) CDH1 / E Cadherin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
E-cadherin (epithelial) / E Cadherin (Antibody to), classification 1, sapiens cadherin 1, Mouse monoclonal [clonality 3F4] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Arc-1 and CD324 and CDHE and ECAD and LCAM and UVO, BT, CDH1 and IDBG-38622 and ENSG00000039068 and 999, Cdh1 and IDBG-190074 and ENSMUSG00000000303 and 12550, DNA-templated and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051260 and protein homooli this GO merization and biological process this GO :0060576 and intestinal epithelial cell development and biological process this GO :0060662 and salivary gland cavitation and biological process this GO :0060693 and regulation of branching involved in salivary gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0071944 and cell periphery and cellular component this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090102 and cochlea development and biological process this GO :2000008 and regulation of protein localization to cell surface and biological process this GO :2001222 and regulation of neuron migration and biological process, E-cadherin (epithelial), Extracellular, cell adhesion molecule binding, this GO :0001701 and in utero embryonic development and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007416 and synapse assembly and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0009636 and response to toxic substance and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010033 and response to organic substance and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016235 and aggresome and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0016342 and catenin complex and cellular component this GO :0019538 and protein metabolic process and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021983 and pituitary gland development and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030054 and cell junction and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030424 and axon and cellular component this GO :0030506 and ankyrin binding and molecular function this GO :0031175 and neuron projection development and biological process this GO :0032794 and GTPase activating protein binding and molecular function this GO :0032880 and regulation of protein localization and biological process this GO :0033268 and node of Ranvier and cellular component this GO :0033561 and regulation of water loss via skin and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042493 and response to drug and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043219 and lateral loop and cellular component this GO :0043220 and Schmidt-Lanterman incisure and cellular component this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043296 and apical junction complex and cellular component this GO :0043679 and axon terminus and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045893 and positive regulation of transcription, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0019903 : protein phosphatase binding and also this GO :0019904 : protein domain specific binding and also this GO :0030506 : ankyrin binding and also this GO :0032794 : GTPase activating protein binding and also this GO :0045295 : gamma-catenin binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0019903 : protein phosphatase binding, this GO :0019904 : protein domain specific binding, this GO :0030506 : ankyrin binding, this GO :0032794 : GTPase activating protein binding, this GO :0045295 : gamma-catenin binding, this GO :0050839 : cell adhesion molecule binding, type 1, 64827 and IDBG-634263 and ENSBTAG00000015991 and 282637, cadherin 1 |
| Identity: |
1748 |
| Gene: |
CDH1 |
More about : CDH1 |
| Long gene name: |
cadherin 1 |
| Synonyms gene: |
UVO |
| Synonyms gene name: |
E-cadherin (epithelial) , cadherin 1, type 1 |
| Synonyms: |
uvomorulin CD324 |
| Synonyms name: |
E-Cadherin |
| Locus: |
16q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
L08599 |
| Entrez gene record: |
999 |
| Pubmed identfication: |
9925936 |
| RefSeq identity: |
NM_004360 |
| Classification: |
Type I classical cadherins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137561 |
| Locus Specific Databases: |
LRG_301 |