| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Proteasome subunit alpha type-1 (PSMA1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PSMA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PSMA1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P25786 |
| Purity: |
Antigen affinity |
| Description: |
2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits, Alternative splicing results in multiple transcript variants encoding distinct isoforms, An essential function of a modified proteasome, Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway, The core structure is composed of 4 rings of 28 non-identical subunits, This gene encodes a member of the peptidase T1A family, is the processing of class I MHC peptides, that is a 20S core alpha subunit, the immunoproteasome, The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure |
| Immunogen: |
A portion of amino acids 234-262 from the human protein was used as the immunogen for this PSMA1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PSMA1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Proteasome subunit alpha 1 (PSMA1) |
| Short name: |
Proteasome subunit alpha type-1 Antibody (PSMA1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
protein degradation aggregate functionnal sequence a classification-1 (Antibody to) (proteasome subunit a classification-1 isoform 3) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HC2 and HEL-S-275 and NU and PROS30, PSMA1 and IDBG-545891 and ENSG00000256206 and 5682, alpha-subunit complex and cellular component this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process, nuclei, this GO :0004175 and endopeptidase activity and molecular function this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0019773 and proteasome core complex, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004298 : threonine-type endopeptidase activity, this GO :0004298 : threonine-type endopeptidase activity, threonine-type endopeptidase activity, proteasome subunit alpha type-1 isoform 3 |
| Identity: |
9530 |
| Gene: |
PSMA1 |
More about : PSMA1 |
| Long gene name: |
proteasome subunit alpha 1 |
| Synonyms gene name: |
1 , alpha type, macropain) subunit, proteasome (prosome |
| Synonyms: |
HC2 NU PROS30 MGC14542 MGC14575 MGC14751 MGC1667 MGC21459 MGC22853 MGC23915 |
| Locus: |
11p15, 2 |
| Discovery year: |
1995-05-03 |
| GenBank acession: |
X61969 |
| Entrez gene record: |
5682 |
| Pubmed identfication: |
1398136 2025653 |
| RefSeq identity: |
NM_002786 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000165825 |