| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BECN1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IF |
| Recommended dilutions: |
Immunofluorescence: 1:100, Western blot: 1:1000 |
| Notes: |
Titration of the BECN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BECN1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14457 |
| Purity: |
Antigen affinity |
| Description: |
[supplied by OMIM], and neurodegeneration, tumorigenesis, Beclin-1 participates in the regulation of autophagy and has an important role in development |
| Immunogen: |
A portion of amino acids 100-123 from the human protein was used as the immunogen for this BECN1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BECN1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BECN1 |
| Short name: |
BECN1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
autophagy related (Antibody to), beclin 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATG6 and beclin1 and VPS30, BECN1 and IDBG-51769 and ENSG00000126581 and 102725513, BECN1 and IDBG-640456 and ENSBTAG00000019914 and 527278, Becn1 and IDBG-212053 and ENSMUSG00000035086 and 56208, Plasma membranes, autophagy related, sequence-specific DNA binding, this GO :0000910 and cytokinesis and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0006914 and autophagy and biological process this GO :0006968 and cellular defense response and biological process this GO :0007040 and lysosome organization and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016239 and positive regulation of macroautophagy and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0048666 and neuron development and biological process this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0051707 and response to other organism and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0043565 : sequence-specific DNA binding, 8678, beclin 1 |
| Identity: |
1034 |
| Gene: |
BECN1 |
More about : BECN1 |
| Long gene name: |
beclin 1 |
| Synonyms gene name: |
autophagy related , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) beclin 1 |
| Synonyms: |
ATG6 VPS30 |
| Synonyms name: |
ATG6 autophagy related 6 homolog (S, cerevisiae) |
| Locus: |
17q21, 31 |
| Discovery year: |
1998-11-27 |
| GenBank acession: |
AF077301 |
| Entrez gene record: |
8678 |
| Pubmed identfication: |
9765397 |
| RefSeq identity: |
NM_003766 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000180653 |