| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCR10 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CCR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CCR10 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P46092 |
| Purity: |
Antigen affinity |
| Description: |
2002 [PubMed 11821900]), CCR10 is the receptor for CCL27 (SCYA27, CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al, CXC and CC, Chemokines also play fundamental roles in the development, Chemokines are divided into 2 major subfamilies, G protein-coupled receptors, MIM 604833), and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis, based on the arrangement of the first 2 of the 4 conserved cysteine residues, homeostasis, mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines, Chemokines are a group of small (approximately 8 to 14 kD) |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR10 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCR10 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCR10 |
| Short name: |
CCR10 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) receptor 10 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-C chemokine receptor activity, CCR10 and IDBG-51414 and ENSG00000184451 and 2826, CCR10 and IDBG-640334 and ENSBTAG00000019095 and 539108, Ccr10 and IDBG-211910 and ENSMUSG00000044052 and 12777, GPR2, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0016493 : C-C chemokine receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0016493 : C-C chemokine receptor activity, chemokine (C-C motif) receptor 10 |
| Identity: |
4474 |
| Gene: |
CCR10 |
More about : CCR10 |
| Long gene name: |
C-C motif chemokine receptor 10 |
| Synonyms gene: |
GPR2 |
| Synonyms gene name: |
G protein-coupled receptor 2 chemokine (C-C motif) receptor 10 |
| Locus: |
17q21, 2 |
| Discovery year: |
1994-07-25 |
| GenBank acession: |
AF215981 |
| Entrez gene record: |
2826 |
| Pubmed identfication: |
7851889 |
| RefSeq identity: |
NM_016602 |
| Classification: |
C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000132301 |