| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Integrin alpha 5 (ITGA5) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the Integrin alpha 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Integrin alpha 5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P08648 |
| Purity: |
Antigen affinity |
| Description: |
Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor, In addition to adhesion, Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, This gene encodes the integrin alpha 5 chain, [provided by RefSeq], integrins are known to participate in cell-surface mediated signalling, The product of this gene belongs to the integrin alpha chain family |
| Immunogen: |
A portion of amino acids 575-602 from the human protein was used as the immunogen for this Integrin alpha 5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Integrin alpha 5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Integrin alpha 5 (ITGA5) |
| Short name: |
Integrin alpha 5 Antibody (ITGA5) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a 5 (fibronectin receptor, a polypeptide)), Integrin a 5 (Antibody to) (integrin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD49e and FNRA and VLA5A, Cell surfaces, ITGA5 and IDBG-37894 and ENSG00000161638 and 3678, Itga5 and IDBG-189590 and ENSMUSG00000000555 and 16402, alpha 5 (fibronectin receptor, alpha polypeptide), cell adhesion molecule binding, spreading of epidermal cells and biological process this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0045202 and synapse and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0071062 and alphav-beta3 integrin-vitronectin complex and cellular component this GO :2000811 and negative regulation of anoikis and biological process, this GO :0001525 and angiogenesis and biological process this GO :0001726 and ruffle and cellular component this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0007044 and cell-substrate junction assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008305 and integrin complex and cellular component this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0016032 and viral process and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031589 and cell-substrate adhesion and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0033631 and cell-cell adhesion mediated by integrin and biological process this GO :0035313 and wound healing, this GO :0005154 : epidermal growth factor receptor binding, this GO :0005154 : epidermal growth factor receptor binding and also this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0043184 : vascular endothelial growth factor receptor 2 binding and also this GO :0046872 : metal ion binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0043184 : vascular endothelial growth factor receptor 2 binding, this GO :0046872 : metal ion binding, this GO :0050839 : cell adhesion molecule binding, 27462 and IDBG-631085 and ENSBTAG00000013745 and 281873, integrin |
| Identity: |
6141 |
| Gene: |
ITGA5 |
More about : ITGA5 |
| Long gene name: |
integrin subunit alpha 5 |
| Synonyms gene: |
FNRA |
| Synonyms gene name: |
alpha 5 (fibronectin receptor, alpha polypeptide) , integrin |
| Synonyms: |
CD49e |
| Synonyms name: |
alpha polypeptide , fibronectin receptor |
| Locus: |
12q13, 13 |
| Discovery year: |
1988-07-19 |
| Entrez gene record: |
3678 |
| Pubmed identfication: |
2454952 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000169841 |