| Also known as: |
ITGA5/Integrin Alpha 5/CD49e |
| Other names: |
CD49 antigen-like family member E, CD49 antigen-like family member E, CD_antigen: CD49eCleaved into the following 2 chains:Integrin alpha-5 heavy chain, Fibronectin receptor subunit alpha, Integrin alpha-5, Integrin alpha-5 light chain, Integrin alpha-F, VLA-5, alpha 5 (fibronectin receptor, alpha polypeptide), alpha subunit, alpha subunit, fibronectin receptor, fibronectin receptor subunit alpha, integrin, integrin alpha-5, integrin alpha-F, very late activation protein 5, integrin alpha-5 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ITGA5 |
| Other gene names: |
CD49e, FNRA, FNRA, ITGA5, VLA-5, VLA5A, ITGA5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
10F6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human ITGA5 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascites fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Mouse Monoclonal [clone 10F6] (IgG2a) ITGA5/Integrin Alpha 5/CD49e Antibody is a &alpha |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 10F6] (IgG2a) ITGA5/Integrin Alpha 5/CD49e |
| Short name: |
Mouse Monoclonal [clone 10F6] (IgG2a) ITGA5/Integrin Alpha 5/CD49e Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
a 5 (fibronectin receptor, a polypeptide)/Integrin a 5/CD49e (Antibody to), sapiens integrin, Mouse monoclonal [clonality 10F6] (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD49e and FNRA and VLA5A, Cell surfaces, ITGA5 and IDBG-37894 and ENSG00000161638 and 3678, Itga5 and IDBG-189590 and ENSMUSG00000000555 and 16402, alpha 5 (fibronectin receptor, alpha polypeptide), cell adhesion molecule binding, spreading of epidermal cells and biological process this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0045202 and synapse and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0071062 and alphav-beta3 integrin-vitronectin complex and cellular component this GO :2000811 and negative regulation of anoikis and biological process, this GO :0001525 and angiogenesis and biological process this GO :0001726 and ruffle and cellular component this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0007044 and cell-substrate junction assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008305 and integrin complex and cellular component this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0016032 and viral process and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031589 and cell-substrate adhesion and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0033631 and cell-cell adhesion mediated by integrin and biological process this GO :0035313 and wound healing, this GO :0005154 : epidermal growth factor receptor binding, this GO :0005154 : epidermal growth factor receptor binding and also this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0043184 : vascular endothelial growth factor receptor 2 binding and also this GO :0046872 : metal ion binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0043184 : vascular endothelial growth factor receptor 2 binding, this GO :0046872 : metal ion binding, this GO :0050839 : cell adhesion molecule binding, 27462 and IDBG-631085 and ENSBTAG00000013745 and 281873, integrin |
| Identity: |
6141 |
| Gene: |
ITGA5 |
More about : ITGA5 |
| Long gene name: |
integrin subunit alpha 5 |
| Synonyms gene: |
FNRA |
| Synonyms gene name: |
alpha 5 (fibronectin receptor, alpha polypeptide) , integrin |
| Synonyms: |
CD49e |
| Synonyms name: |
alpha polypeptide , fibronectin receptor |
| Locus: |
12q13, 13 |
| Discovery year: |
1988-07-19 |
| Entrez gene record: |
3678 |
| Pubmed identfication: |
2454952 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000169841 |