SDHD Antibody

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Catalog number: F41948-0.4ML
Price: 1862 €
Supplier: MBS Recombinant Proteins
Product name: SDHD Antibody
Quantity: 1000ug
Other quantities: 0.08 ml 199€ 0.1ml 263€ 100ug 431€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: SDHD
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IF, IHC, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the SDHD antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This SDHD antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: O14521
Purity: Antigen affinity
Description: Mutations in SDHD have been linked to hereditary paraganglioma, The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane, The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane, carries electrons from FADH to CoQ, which is specifically involved in the oxidation of succinate, Complex II of the respiratory chain
Immunogen: A portion of amino acids 13-42 from the human protein was used as the immunogen for this SDHD antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SDHD antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: SDHD
Short name: SDHD Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: SDHD (Antibody to)
Alternative technique: antibodies
Identity: 10683
Gene: SDHD | More about : SDHD
Long gene name: succinate dehydrogenase complex subunit D
Synonyms gene: PGL PGL1
Synonyms gene name: integral membrane protein , subunit D, succinate dehydrogenase complex
Synonyms: cybS
Synonyms name: small subunit of cytochrome b
Locus: 11q23
Discovery year: 1997-10-21
GenBank acession: AB006202
Entrez gene record: 6392
Pubmed identfication: 9533030 1301144
RefSeq identity: NM_003002
Classification: Mitochondrial complex II: succinate dehydrogenase subunits
Havana BLAST/BLAT: OTTHUMG00000166997
Locus Specific Databases: SDHD @ LOVD TCA Cycle Gene Mutation Database LRG_9

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