| Catalog number: | F41948-0.08ML |
|---|---|
| Price: | 1862 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | SDHD Antibody |
| Quantity: | 1000ug |
| Other quantities: | 0.1ml 263€ 0.4 ml 406€ 100ug 431€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | SDHD |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: | Titration of the SDHD antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This SDHD antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | O14521 |
| Purity: | Antigen affinity |
| Description: | Mutations in SDHD have been linked to hereditary paraganglioma, The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane, The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane, carries electrons from FADH to CoQ, which is specifically involved in the oxidation of succinate, Complex II of the respiratory chain |
| Immunogen: | A portion of amino acids 13-42 from the human protein was used as the immunogen for this SDHD antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SDHD antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | SDHD |
| Short name: | SDHD Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | SDHD (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 10683 |
| Gene: | SDHD | More about : SDHD |
| Long gene name: | succinate dehydrogenase complex subunit D |
| Synonyms gene: | PGL PGL1 |
| Synonyms gene name: | integral membrane protein , subunit D, succinate dehydrogenase complex |
| Synonyms: | cybS |
| Synonyms name: | small subunit of cytochrome b |
| Locus: | 11q23 |
| Discovery year: | 1997-10-21 |
| GenBank acession: | AB006202 |
| Entrez gene record: | 6392 |
| Pubmed identfication: | 9533030 1301144 |
| RefSeq identity: | NM_003002 |
| Classification: | Mitochondrial complex II: succinate dehydrogenase subunits |
| Havana BLAST/BLAT: | OTTHUMG00000166997 |
| Locus Specific Databases: | SDHD @ LOVD TCA Cycle Gene Mutation Database LRG_9 |
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