| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SUV39H1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the SUV39H1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This SUV39H1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O43463 |
| Purity: |
Purified |
| Description: |
About 27 are grouped into the SET-domain family, Five members have been identified in the arginine methyltransferase family, Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, RIZ1 is also a tumor susceptibility gene in mice, The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island, The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family, and another 17 make up the PR domain family that is related to the SET domain family, and lung cancer cell lines as well as in liver cancer tissues, and missense mutation, chromosomal deletion, colon, frame shift mutation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity, liver, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family, Similar to acetylation and phosphorylation |
| Immunogen: |
N-terminal purified recombinant protein was used as the immunogen for the SUV39H1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SUV39H1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SUV39H1 |
| Short name: |
SUV39H1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SUV39H1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11479 |
| Gene: |
SUV39H1 |
More about : SUV39H1 |
| Long gene name: |
suppressor of variegation 3-9 homolog 1 |
| Synonyms gene: |
SUV39H |
| Synonyms gene name: |
suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila) |
| Synonyms: |
KMT1A |
| Locus: |
Xp11, 23 |
| Discovery year: |
1996-04-12 |
| GenBank acession: |
AF019968 |
| Entrez gene record: |
6839 |
| Pubmed identfication: |
10202156 |
| RefSeq identity: |
NM_003173 |
| Classification: |
Lysine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000022701 |
| Locus Specific Databases: |
Mental Retardation database |