| Long name: |
ALEXA FLUOR 594 Conjugated, SUV39H1 Polyclonal Antibody |
| Also known as: |
Anti-SUV39H1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SUV39H1 |
| Specificity: |
This is a highly specific antibody against SUV39H1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1 |
| Gene ID Number: |
6839 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BMP-induced repression, Component of the eNoSC (energy-dependent nucleolar silencing) complex, The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, repression of switch recombination to IgA and regulation of telomere length, such as repression of MYOD1-stimulated differentiation, SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KMT1A |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SUV39H1 |
| Short name: |
SUV39H1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, SUV39H1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11479 |
| Gene: |
SUV39H1 |
More about : SUV39H1 |
| Long gene name: |
suppressor of variegation 3-9 homolog 1 |
| Synonyms gene: |
SUV39H |
| Synonyms gene name: |
suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila) |
| Locus: |
Xp11, 23 |
| Discovery year: |
1996-04-12 |
| GenBank acession: |
AF019968 |
| Entrez gene record: |
6839 |
| Pubmed identfication: |
10202156 |
| RefSeq identity: |
NM_003173 |
| Classification: |
Lysine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000022701 |
| Locus Specific Databases: |
Mental Retardation database |