MITF Antibody

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Catalog number: F41536-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: MITF Antibody
Quantity: 0.08 ml
Other quantities: 0.1ml 263€ 0.4 ml 406€ 1 mililiter Concentrate 779€ 1 vial 411€ 100ul Concentrate 265€ 15 ml 779€ 3 ml 326€ 5 + Control Slides 304€ 500ul Concentrate 509€ 7 ml 481€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: MITF
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IF, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000-2000
Notes: Titration of the MITF antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This MITF antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: O75030
Purity: Antigen affinity
Description: Alternatively spliced transcript variants encoding different isoforms have been identified, Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes, such as Waardenburg syndrome type 2 and Tietz syndrome, This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features
Immunogen: A portion of amino acids 1-28 from the human protein was used as the immunogen for this MITF antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MITF antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: MITF
Short name: MITF Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: microphthalmia-associated transcription factor (Antibody to)
Alternative technique: antibodies
Alternative to gene target: BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0030154 and cell differentiation and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0030318 and melanocyte differentiation and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043473 and pigmentation and biological process this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046849 and bone remodeling and biological process this GO :0046983 and protein dimerization activity and molecular function, MITF and IDBG-44086 and ENSG00000187098 and 4286, Mitf and IDBG-172461 and ENSMUSG00000035158 and 17342, bHLHe32 and CMM8 and MI and WS2 and WS2A, nuclei, protein dimerization activity, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0046983 : protein dimerization activity, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0046983 : protein dimerization activity, 29882 and IDBG-644985 and ENSBTAG00000006679 and 407219, microphthalmia-associated transcription factor
Identity: 7105
Gene: MITF | More about : MITF
Long gene name: melanogenesis associated transcription factor
Synonyms gene: WS2A WS2
Synonyms gene name: Waardenburg syndrome, type 2A microphthalmia-associated transcription factor
Synonyms: MI bHLHe32
Synonyms name: homolog of mouse microphthalmia
Locus: 3p13
Discovery year: 1993-10-27
Entrez gene record: 4286
Pubmed identfication: 8069297 7874167 7951321
RefSeq identity: NM_198159
Classification: Basic helix-loop-helix proteins
Havana BLAST/BLAT: OTTHUMG00000149921
Locus Specific Databases: LOVD - Leiden Open Variation Database LRG_776

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