Specificity Protein 1 Antibody (SP1)

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Catalog number: F41459-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: Specificity Protein 1 Antibody (SP1)
Quantity: 0.08 ml
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: Specificity Protein 1 (SP1)
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IF, IHC, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This SP1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P08047
Purity: Antigen affinity
Description: Binds also the PDGFR-alpha G-box promoter, Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, Highly regulated by post-translational modifications (phosphorylations, Implicated in chromatin remodeling, May have a role in modulating the cellular response to DNA damage, Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, Plays an essential role in the regulation of FE65 gene expression, [UniProt], apoptosis, differentiation and immune responses, glycosylation and acetylation), proteolytic cleavage, sumoylation, Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
Immunogen: A portion of amino acids 677-707 from the human protein was used as the immunogen for this SP1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SP1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: Protein 1 (SP1)
Short name: Protein 1 Antibody (SP1)
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: Specificity Protein 1 (Antibody to) (SP1)
Alternative technique: antibodies
Identity: 11205
Gene: SP1 | More about : SP1
Long gene name: Sp1 transcription factor
Synonyms name: specificity protein 1
Locus: 12q13, 13
Discovery year: 1991-06-04
GenBank acession: J03133
Entrez gene record: 6667
Pubmed identfication: 1662663
Classification: Sp transcription factors Zinc fingers C2H2-type
Havana BLAST/BLAT: OTTHUMG00000170047

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