| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HNF1B |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the HNF1B antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This HNF1B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35680 |
| Purity: |
Antigen affinity |
| Description: |
Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, The gene has been shown to function in nephron development, The protein binds to DNA as either a homodimer, and expression of this gene is altered in some types of cancer, and regulates development of the embryonic pancreas, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha, This gene encodes a member of the homeodomain-containing superfamily of transcription factors |
| Immunogen: |
A portion of amino acids 498-529 from the human protein was used as the immunogen for this HNF1B antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HNF1B antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HNF1B |
| Short name: |
HNF1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HNF1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11630 |
| Gene: |
HNF1B |
More about : HNF1B |
| Long gene name: |
HNF1 homeobox B |
| Synonyms gene: |
TCF2 |
| Synonyms gene name: |
LF-B3, hepatic, transcription factor 2, variant hepatic nuclear factor |
| Synonyms: |
LFB3 VHNF1 HNF1beta MODY5 |
| Locus: |
17q12 |
| Discovery year: |
1990-05-28 |
| GenBank acession: |
BC017714 |
| Entrez gene record: |
6928 |
| Pubmed identfication: |
1677179 10484768 |
| RefSeq identity: |
NM_000458 |
| Classification: |
HNF class homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000188478 |