HDAC1 Antibody

Contact us
Catalog number: F41123-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: HDAC1 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 389€ 0.1ml 263€ 0.4 ml 406€ 1 tube 648€ 1 vial 521€ 1 x 1 vial 411€ 100ul 707€ 50ug 514€
Related search:

More details :

Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: HDAC1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IF, WB
Recommended dilutions: Immunofluorescence: 1:10-1:50, Western blot: 1:1000-2000
Notes: Titration of the HDAC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This HDAC1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q13547
Purity: Purified
Description: Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, Component of the BRG1-RB1-HDAC1 complex, Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B, Deacetylates NR1D2 and abrogates the effect of KAT5-mediated relieving of NR1D2 transcription repression activity, Deacetylates SP proteins, Deacetylates TSHZ3 and regulates its transcriptional repressor activity, H2B, H3 and H4), HDAC1 is released from the complex and CREBBP is recruited, Histone deacetylases act via the formation of large multiprotein complexes, Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, Involved in CIART-mediated transcriptional repression of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer, Required for the transcriptional repression of circadian target genes, SP1 and SP3, Upon calcium stimulation, [UniProt], a number of genes implicated in multilineage blood cell development, and regulates their function, cell cycle progression and developmental events, mediated by the large PER complex or CRY1 through histone deacetylation, such as PER1, via histone deacetylase (HDAC) recruitment, which facilitates transcriptional activation, which negatively regulates the CREST-mediated transcription in resting neurons, HDAC1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A
Immunogen: A portion of amino acids 449-482 from the human protein was used as the immunogen for this HDAC1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HDAC1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: HDAC1
Short name: HDAC1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: histone deacetylase 1 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009913 and epidermal cell differentiation and biological process this GO :0010467 and gene expression and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0016032 and viral process and biological process this GO :0016568 and chromatin modification and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016580 and Sin3 complex and cellular component this GO :0016581 and NuRD complex and cellular component this GO :0019213 and deacetylase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0031492 and nucleosomal DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0033613 and activating transcription factor binding and molecular function this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043044 and ATP-dependent chromatin remodeling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0061198 and fungiform papilla formation and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function, HDAC1 and IDBG-644586 and ENSBTAG00000012698 and 404126, HDAC1 and IDBG-95712 and ENSG00000116478 and 3065, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0001106 and RNA polymerase II transcription corepressor activity and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000976 : transcription regulatory region sequence-specific DNA binding, this GO :0000976 : transcription regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001047 : core promoter binding and also this GO :0001103 : RNA polymerase II repressing transcription factor binding and also this GO :0001106 : RNA polymerase II transcription corepressor activity and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019213 : deacetylase activity and also this GO :0019899 : enzyme binding and also this GO :0031492 : nucleosomal DNA binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558 : protein deacetylase activity and also this GO :0033613 : activating transcription factor binding and also this GO :0042826 : histone deacetylase binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001047 : core promoter binding, this GO :0001103 : RNA polymerase II repressing transcription factor binding, this GO :0001106 : RNA polymerase II transcription corepressor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019213 : deacetylase activity, this GO :0019899 : enzyme binding, this GO :0031492 : nucleosomal DNA binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558 : protein deacetylase activity, this GO :0033613 : activating transcription factor binding, this GO :0042826 : histone deacetylase binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO N-10 and HD1 and RPD3 and RPD3L1, histone deacetylase 1
Identity: 4852
Gene: HDAC1 | More about : HDAC1
Long gene name: histone deacetylase 1
Synonyms gene: RPD3L1
Synonyms: HD1 GON-10
Locus: 1p35, 1 , 2-p35
Discovery year: 1996-11-15
GenBank acession: D50405
Entrez gene record: 3065
Pubmed identfication: 8602529
RefSeq identity: NM_004964
Classification: NuRD complex Histone deacetylases, class I EMSY complex SIN3 histone deacetylase complex
Havana BLAST/BLAT: OTTHUMG00000007529

Related Products :