| known also as: |
KIAA0929, MINT, Msx2-interacting Nuclear Target (MINT) Homolog, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul, SMART/HDAC1-associated Repressor Protein, Anti-SHARP (SMART/HDAC1 Associated Repressor Protein |
| known also as: |
KIAA0929, MINT, Msx2-interacting Nuclear Target (MINT) Homolog, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul, SMART/HDAC1-associated Repressor Protein, SHARP (SMART/HDAC1 Associated Repressor Protein |
| known also as: |
KIAA0929, MINT, Msx2-interacting Nuclear Target (MINT) Homolog, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul, SMART/HDAC1-associated Repressor Protein, SHARP (SMART/HDAC1 Associated Repressor Protein |
| known also as: |
SHARP |
| known also as: |
KIAA0929, MINT, Msx2-interacting Nuclear Target (MINT) Homolog, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul, SMART/HDAC1-associated Repressor Protein, Anti -SHARP (SMART/HDAC1 Associated Repressor Protein |
| Other names: |
N/A, Small histidine-alanine-rich protein |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: Human |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
pH 7 to 8, Tris-citrate/phosphate buffer |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
KIAA0929, MINT, Msx2-interacting (MINT) Homolog, Msx2-interacting Protein, Receptor Transcription Cofactor Spen Homolog Transcriptional Regul, SMART/HDAC1-associated Repressor Protein, SHARP (SMART/HDAC1 Associated Repressor Protein |
| Short name: |
KIAA0929, MINT, Msx2-interacting Nuclear (MINT) Homolog, Msx2-interacting Protein, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul Antibody, SMART/HDAC1-associated Repressor Protein, SHARP (SMART/HDAC1 Associated Repressor Protein |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KIAA0929, MINT, Nuclear Receptor Transcription Cofactor Spen Homolog Transcriptional Regul (Antibody to), SMART/histone deacetylase 1-associated Repressor Protein, msh homeobox 2-interacting Nuclear Target (MINT) Homolog, msh homeobox 2-interacting Protein, SHARP (SMART/histone deacetylase 1 Associated Repressor Protein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009913 and epidermal cell differentiation and biological process this GO :0010467 and gene expression and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0016032 and viral process and biological process this GO :0016568 and chromatin modification and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016580 and Sin3 complex and cellular component this GO :0016581 and NuRD complex and cellular component this GO :0019213 and deacetylase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0031492 and nucleosomal DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0033613 and activating transcription factor binding and molecular function this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043044 and ATP-dependent chromatin remodeling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0061198 and fungiform papilla formation and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function, HDAC1 and IDBG-644586 and ENSBTAG00000012698 and 404126, HDAC1 and IDBG-95712 and ENSG00000116478 and 3065, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0001106 and RNA polymerase II transcription corepressor activity and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000976 : transcription regulatory region sequence-specific DNA binding, this GO :0000976 : transcription regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001047 : core promoter binding and also this GO :0001103 : RNA polymerase II repressing transcription factor binding and also this GO :0001106 : RNA polymerase II transcription corepressor activity and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019213 : deacetylase activity and also this GO :0019899 : enzyme binding and also this GO :0031492 : nucleosomal DNA binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558 : protein deacetylase activity and also this GO :0033613 : activating transcription factor binding and also this GO :0042826 : histone deacetylase binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001047 : core promoter binding, this GO :0001103 : RNA polymerase II repressing transcription factor binding, this GO :0001106 : RNA polymerase II transcription corepressor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019213 : deacetylase activity, this GO :0019899 : enzyme binding, this GO :0031492 : nucleosomal DNA binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558 : protein deacetylase activity, this GO :0033613 : activating transcription factor binding, this GO :0042826 : histone deacetylase binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO N-10 and HD1 and RPD3 and RPD3L1, histone deacetylase 1 |
| Identity: |
17575 |
| Gene: |
SPEN |
More about : SPEN |
| Long gene name: |
spen family transcriptional repressor |
| Synonyms gene name: |
SPEN homolog, transcriptional regulator (Drosophila) , transcriptional regulator (Drosophila) spen homolog |
| Synonyms: |
KIAA0929 MINT SHARP RBM15C |
| Locus: |
1p36, 13 , 21-p36 |
| Discovery year: |
2004-12-13 |
| Entrez gene record: |
23013 |
| Pubmed identfication: |
10451362 11331609 |
| RefSeq identity: |
NM_015001 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000009376 |