AKT1 Antibody

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Catalog number: F40742-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: AKT1 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 406€ 0.4 ml 406€ 1 vial 486€ 1 x 1 vial 486€ 100ug 370€ 50ug 299€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: AKT1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, WB, IHC
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
Notes: Titration of the AKT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This AKT1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P31749
Purity: Antigen affinity
Description: AKT1 and the related AKT2 are activated by platelet-derived growth factor, In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival, It was shown that the activation occurs through phosphatidylinositol 3-kinase, Multiple alternatively spliced transcript variants have been found for this gene, Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, The activation is rapid and specific, [provided by RefSeq], and it is abrogated by mutations in the pleckstrin homology domain of AKT1, which then phosphorylates and inactivates components of the apoptotic machinery, The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts
Immunogen: A portion of amino acids 282-309 from the human protein was used as the immunogen for this AKT1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AKT1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: AKT1
Short name: AKT1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: v-akt murine thymoma viral oncogene homolog 1 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: AKT and CWS6 and PKB and PKB-ALPHA and PRKBA and RAC and RAC-ALPHA, AKT1 and IDBG-22709 and ENSG00000142208 and 207, AKT1 and IDBG-635767 and ENSBTAG00000017636 and, Akt1 and IDBG-174623 and ENSMUSG00000001729 and 11651, nuclei, phosphatidylinositol-3, this GO :0000060 and protein import into nucleus, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005547 : phosphatidylinositol-3, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0030235 : nitric-oxide synthase regulator activity, this GO :0042802 : identical protein binding, this GO :0043325 : phosphatidylinositol-3, this GO :0071889 : 14-3-3 protein binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0030235 : nitric-oxide synthase regulator activity and also this GO :0042802 : identical protein binding and also this GO :0043325 : phosphatidylinositol-3, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030030 and cell projection organization and biological process this GO :0030154 and cell differentiation and biological process this GO :0030163 and protein catabolic process and biological process this GO :0030168 and platelet activation and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030235 and nitric-oxide synthase regulator activity and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0031295 and T cell costimulation and biological process this GO :0031659 and positive regulation of cyclin-dependent protein kinase activity involved in G1/S and biological process this GO :0031999 and negative regulation of fatty acid beta-oxidation and biological process this GO :0032094 and response to food and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032880 and regulation of protein localization and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034405 and response to fluid shear stress and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042640 and anagen and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043325 and phosphatidylinositol-3, translocation and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001893 and maternal placenta development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005547 and phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding and also this GO :0071889 : 14-3-3 protein binding, 4-bisphosphate binding and molecular function this GO :0043491 and protein kinase B signaling and biological process this GO :0043536 and positive regulation of blood vessel endothelial cell migration and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046889 and positive regulation of lipid biosynthetic process and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060709 and glycogen cell differentiation involved in embryonic placenta development and biological process this GO :0060716 and labyrinthine layer blood vessel development and biological process this GO :0061024 and membrane organization and biological process this GO :0070141 and response to UV-A and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071889 and 14-3-3 protein binding and molecular function this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :0097011 and cellular response to granulocyte macrophage colony-stimulating factor stimulus and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901653 and cellular response to peptide and biological process this GO :1901976 and regulation of cell cycle checkpoint and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, 5-trisphosphate binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005819 and spindle and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005977 and glycogen metabolic process and biological process this GO :0005978 and glycogen biosynthetic process and biological process this GO :0005979 and regulation of glycogen biosynthetic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006412 and translation and biological process this GO :0006417 and regulation of translation and biological process this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0007568 and aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0009408 and response to heat and biological process this GO :0009725 and response to hormone and biological process this GO :0010467 and gene expression and biological process this GO :0010507 and negative regulation of autophagy and biological process this GO :0010748 and negative regulation of plasma membrane long-chain fatty acid transport and biological process this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0010975 and regulation of neuron projection development and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0015758 and glucose transport and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016772 and transferase activity, v-akt murine thymoma viral oncogene homolog 1
Identity: 391
Gene: AKT1 | More about : AKT1
Long gene name: AKT serine/threonine kinase 1
Synonyms gene name: v-akt murine thymoma viral oncogene homolog 1
Synonyms: RAC PKB PRKBA AKT
Locus: 14q32, 33
Discovery year: 1986-01-01
GenBank acession: M63167
Entrez gene record: 207
RefSeq identity: NM_005163
Classification: Pleckstrin homology domain containing
Havana BLAST/BLAT: OTTHUMG00000170795
Locus Specific Databases: LRG_721

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