| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PRMT5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PRMT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PRMT5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O14744 |
| Purity: |
Purified |
| Description: |
At least three types of PRMT enzymes have been identified in mammalian cells, IL enhancer binding factor, Outside of these domains, The mammalian PRMT family currently consists of 7 members that share two large domains of homology, These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas, These protein include nuclear proteins, and viral proteins, apoptosis proteins, cell cycle proteins, epitopes were identified and antibodies against all 7 PRMT members have been developed, nuclear factors, signal transduction proteins, Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity |
| Immunogen: |
A portion of amino acids 473-499 from the human protein was used as the immunogen for this PRMT5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PRMT5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PRMT5 |
| Short name: |
PRMT5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PRMT5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10894 |
| Gene: |
PRMT5 |
More about : PRMT5 |
| Long gene name: |
protein arginine methyltransferase 5 |
| Synonyms gene: |
HRMT1L5 SKB1 |
| Synonyms gene name: |
pombe) , pombe) homolog SKB1 homolog (S, skb1 (S |
| Synonyms: |
SKB1Hs |
| Locus: |
14q11, 2 |
| Discovery year: |
1999-06-18 |
| GenBank acession: |
AF015913 |
| Entrez gene record: |
10419 |
| Pubmed identfication: |
9843966 |
| Classification: |
Protein arginine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000028709 |