| Long name: |
ALEXA FLUOR 647 Conjugated, PRMT5 Polyclonal Antibody |
| Also known as: |
Anti-PRMT5 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRMT5 |
| Specificity: |
This is a highly specific antibody against PRMT5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRMT5 |
| Gene ID Number: |
10419 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
May be part of a pathway that is connected to a chloride current, May play a role in cytokine-activated transduction pathways, May regulate the SUPT5H transcriptional elongation properties, Methylates RPS10, Methylates SUPT5H, Methylates histone H2A and H4 'Arg-3' during germ cell development, Methylates histone H3 'Arg-8', Methylates the Piwi proteins (PIWIL1, Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro, Negatively regulates cyclin E1 promoter activity and cellular proliferation, PIWIL2 and PIWIL4), Plays a role in the assembly of snRNP core particles, Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage, possibly through cytoskeletal rearrangement, such methylation being required for the assembly and biogenesis of snRNP core particles, which may repress transcription, with a preference for the formation of MMA, Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SKB1Hs |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PRMT5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PRMT5 |
| Short name: |
PRMT5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, PRMT5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10894 |
| Gene: |
PRMT5 |
More about : PRMT5 |
| Long gene name: |
protein arginine methyltransferase 5 |
| Synonyms gene: |
HRMT1L5 SKB1 |
| Synonyms gene name: |
pombe) , pombe) homolog SKB1 homolog (S, skb1 (S |
| Locus: |
14q11, 2 |
| Discovery year: |
1999-06-18 |
| GenBank acession: |
AF015913 |
| Entrez gene record: |
10419 |
| Pubmed identfication: |
9843966 |
| Classification: |
Protein arginine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000028709 |