| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RSKB (MSK2) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the RSKB antibody (MSK2) may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This RSKB antibody (MSK2)is to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O75676 |
| Purity: |
Purified |
| Description: |
By this basic mechanism, CAMKL, DAPK, MAPKAPK), PKG) family, The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA &, The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains, With more than 500 gene products, and differentiation, and the kinases that phosphorylate ribosomal protein S6 family (RSK), apoptosis, cell cycle progression, cytoskeletal rearrangement and cell movement, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the kinases that phosphorylate G protein-coupled receptors family (ARK), the protein kinase family is one of the largest families of proteins in eukaryotes, the related to PKA and PKC (RAC/Akt) protein kinase family, transcription, Protein kinases are enzymes that transfer a phosphate group from a phosphate donor |
| Immunogen: |
A portion of amino acids 322-354 from the human protein was used as the immunogen for this RSKB antibody (MSK2) |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RSKB antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RSKB (MSK2) |
| Short name: |
RSKB Antibody (MSK2) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RSKB (Antibody to) (MSK2) |
| Alternative technique: |
antibodies |
| Identity: |
10433 |
| Gene: |
RPS6KA4 |
More about : RPS6KA4 |
| Long gene name: |
ribosomal protein S6 kinase A4 |
| Synonyms gene name: |
90kD, polypeptide 4 , ribosomal protein S6 kinase |
| Synonyms: |
RSK-B MSK2 |
| Locus: |
11q13, 1 |
| Discovery year: |
1999-03-10 |
| GenBank acession: |
AJ010119 |
| Entrez gene record: |
8986 |
| Pubmed identfication: |
9792677 9687510 |
| RefSeq identity: |
NM_003942 |
| Classification: |
Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000046094 |