| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ASAH2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the ASAH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ASAH2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9NR71 |
| Purity: |
Antigen affinity |
| Description: |
2001 [PubMed 11328816]), Sphingosine exerts both mitogenic and apoptosis-inducing activities, a second messenger in a variety of cellular events, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al, catalyze hydrolysis of the N-acyl linkage of ceramide, such as ASAH2, to produce sphingosine, 1, 23), 5, Ceramidases (EC 3 |
| Immunogen: |
A portion of amino acids 734-762 from the human protein was used as the immunogen for this ASAH2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ASAH2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ASAH2 |
| Short name: |
ASAH2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
N-acylsphin this GO sine amidohydrolase (non-lysosomal ceramidase) 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ASAH2 and IDBG-74349 and ENSG00000188611 and 56624, Plasma membranes, ceramidase activity, this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006665 and sphin this GO lipid metabolic process and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006687 and glycosphin this GO lipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0017040 and ceramidase activity and molecular function this GO :0044281 and small molecule metabolic process and biological process, this GO :0017040 : ceramidase activity, this GO :0017040 : ceramidase activity, N-acylsphin this GO sine amidohydrolase (non-lysosomal ceramidase) 2 |
| Identity: |
18860 |
| Gene: |
ASAH2 |
More about : ASAH2 |
| Long gene name: |
N-acylsphingosine amidohydrolase 2 |
| Synonyms gene name: |
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 |
| Synonyms name: |
neutral ceramidase non-lysosomal ceramidase |
| Locus: |
10q11, 23 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF250847 |
| Entrez gene record: |
56624 |
| Pubmed identfication: |
10781606 |
| RefSeq identity: |
NM_019893 |
| Havana BLAST/BLAT: |
OTTHUMG00000018223 |