| Gene info: |
PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, This PTP possesses an extracellular region, This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, a single transmembrane region, and a single catalytic domain, and oncogenic transformation, and thus may be a potential target of autoimmunity in diabetes mellitus, and thus represents a receptor-type PTP, differentiation, mitotic cycle, The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family |
| Gene names: |
ICA512, Islet cell antigen 512, PTPRN protein, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N, ICA3 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
214-332 |
| Immuno application: |
Western Blot |
| Antibody advice: |
PTPRN protein antibody can be used for the detection of PTPRN protein by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, PTPRN antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
4506321 |
| Ncbi nr: |
1, NP_002837 |
| KDa: |
8 kDa (calculated), 87 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
5798 |
| GENE symbol: |
PTPRN |
| Antigene name: |
N, receptor type, protein tyrosine phosphatase |
| Source: |
Homo sapiens |
| Protein nr: |
Q16849 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
PTPRN |
| Short name: |
anti-PTPRN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
N (Antibody to), receptor classification, antibody to-protein tyrosine phosphatase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GTPase binding, IA-2 and IA-2/PTP and IA2 and ICA512 and R-PTP-N, N, PTPRN and IDBG-643992 and ENSBTAG00000013798 and 286810, PTPRN and IDBG-81527 and ENSG00000054356 and 5798, Plasma membranes, Ptprn and IDBG-170581 and ENSMUSG00000026204 and 19275, receptor type, this GO :0000302 and response to reactive oxygen species and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005001 and transmembrane receptor protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0009749 and response to glucose and biological process this GO :0016020 and membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030507 and spectrin binding and molecular function this GO :0032868 and response to insulin and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0043627 and response to estrogen and biological process this GO :0051020 and GTPase binding and molecular function this GO :0051591 and response to cAMP and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0030507 : spectrin binding and also this GO :0051020 : GTPase binding, this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0030507 : spectrin binding, this GO :0051020 : GTPase binding, protein tyrosine phosphatase |
| Identity: |
9676 |
| Gene: |
PTPRN |
More about : PTPRN |
| Long gene name: |
protein tyrosine phosphatase, receptor type N |
| Synonyms: |
IA-2 |
| Locus: |
2q35 |
| Discovery year: |
1995-02-17 |
| Entrez gene record: |
5798 |
| Pubmed identfication: |
8024693 |
| Classification: |
Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000133129 |