| Also known as: |
PTPRN / IA-2 |
| Other names: |
ICA 512, ICA 512, Islet cell antigen 512, Islet cell autoantigen 3, N, PTP IA-2, PTP IA-2, Receptor-type tyrosine-protein phosphatase-like N, islet cell antigen 2, islet cell antigen 512, islet cell autoantigen 3, protein tyrosine phosphatase, protein tyrosine phosphatase-like N, receptor type, receptor-type tyrosine-protein phosphatase-like N, receptor-type tyrosine-protein phosphatase-like N isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PTPRN |
| Gene name synonims: |
IA-2 |
| Other gene names: |
IA-2, IA-2/PTP, IA2, ICA 512, ICA3, ICA512, ICA512, PTPRN, R-PTP-N, R-PTP-N, PTPRN |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
8000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human PTPRN |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 8E3] (IgG2a, k) PTPRN / IA-2 |
| Short name: |
Mouse Monoclonal [clone 8E3] (IgG2a, k) PTPRN / IA-2 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
N / IA-2 (Antibody to), receptor classification, sapiens protein tyrosine phosphatase, Mouse monoclonal [clonality 8E3] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GTPase binding, IA-2 and IA-2/PTP and IA2 and ICA512 and R-PTP-N, N, PTPRN and IDBG-643992 and ENSBTAG00000013798 and 286810, PTPRN and IDBG-81527 and ENSG00000054356 and 5798, Plasma membranes, Ptprn and IDBG-170581 and ENSMUSG00000026204 and 19275, receptor type, this GO :0000302 and response to reactive oxygen species and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005001 and transmembrane receptor protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0009749 and response to glucose and biological process this GO :0016020 and membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030507 and spectrin binding and molecular function this GO :0032868 and response to insulin and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0043627 and response to estrogen and biological process this GO :0051020 and GTPase binding and molecular function this GO :0051591 and response to cAMP and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0030507 : spectrin binding and also this GO :0051020 : GTPase binding, this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0030507 : spectrin binding, this GO :0051020 : GTPase binding, protein tyrosine phosphatase |
| Identity: |
9676 |
| Gene: |
PTPRN |
More about : PTPRN |
| Long gene name: |
protein tyrosine phosphatase, receptor type N |
| Synonyms: |
IA-2 |
| Locus: |
2q35 |
| Discovery year: |
1995-02-17 |
| Entrez gene record: |
5798 |
| Pubmed identfication: |
8024693 |
| Classification: |
Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000133129 |