| Gene info: |
2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, PLK is also required for bipolar spindle formation, Recent work (Erikson, Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK, Ser486 and Ser490), Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482, activation of the anaphase-promoting complex/cyclosome, and cytokinesis, et al, 486, 490 in PLKK, Considerable evidence indicates that a Polo-Like Kinase (PLK) plays an important role in cell cycle regulation |
| Gene names: |
PLK-1, Plx1, plx1, plk |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Affinity Purified |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Spicific to: |
486, 490, PLKK antibody is specific for PLKK phosphorylated at Ser482 |
| Antigen: |
486, 490 PLKK, PLKK (Ser482/486/490) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the Xenopus Phospho-Ser482 |
| Immuno application: |
Western Blot |
| Antibody advice: |
Suitability for Immunohistochemistry (IHC) has not yet been determined, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, Xenopus is the only species tested to date, Applications include Dot Blots (DB) and Western Blots (WB) |
| Suspention, pH, azide: |
100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5) |
| Keep at: |
Stable for one year, but shorter term storage at &ndash, 20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, 80 grades C is recommended, For long term storage &ndash |
| Works with: |
Xenopus |
| Omim nr: |
49036444 |
| Ncbi nr: |
P70032 |
| KDa: |
120 |
| Vial with antibody: |
in solution |
| NCBI GENE nr: |
380481 |
| GENE symbol: |
plk1 |
| Antigene name: |
polo-like kinase 1 |
| Source: |
Xenopus laevis |
| Protein nr: |
P70032 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
PLKK (phospho Ser482 / Ser486 / Ser490) |
| Short name: |
anti-PLKK (phospho Ser482 / Ser486 / Ser490) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-PLKK (phosphorilated Ser482 / Ser486 / Ser490) (Antibody to) |
| Alternative technique: |
antibodies |