| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PGCP |
| Specificity: |
This antibody reacts specifically with PGCP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PGCP |
| Gene ID: |
10404 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Due to its upregulation in hepatocellular carcinoma (HCC), It is a Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides, PGCP is a carboxypeptidase that potentially is involved in the hydrolysis of circulating peptides, PGCP is a member of the Peptidase M28 family of proteins, PGCP is found principally in blood plasma, The gene encoding PGCP maps to chromosome 8, Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis, it is suspected that PGCP may be a potential serological marker for HCC, metallopeptidases and aminopeptidases, which also includes PSM (prostate-specific membrane antigen), which is made up of nearly 146 million bases and encodes about 800 genes, In humans, PGCP is a 472 amino acid secreted protein that is primarily detected in blood plasma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LDP PGCP |
| Also known as: |
PGCP Polyclonal Antibody |
| Other name: |
Anti-PGCP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PGCP |
| Short name: |
Anti-PGCP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PGCP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16910 |
| Gene: |
CPQ |
More about : CPQ |
| Long gene name: |
carboxypeptidase Q |
| Synonyms name: |
lysosomal dipeptidase Ser-Met dipeptidase plasma glutamate carboxypeptidase |
| Locus: |
8q22, 1 |
| Discovery year: |
2012-02-17 |
| GenBank acession: |
AF107834 |
| Entrez gene record: |
10404 |
| Pubmed identfication: |
10206990 |
| RefSeq identity: |
NM_016134 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000164690 |