| Long name: |
Biotin Conjugated, PGCP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PGCP |
| Specificity: |
This is a highly specific antibody against PGCP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PGCP |
| Gene ID number: |
10404 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Due to its upregulation in hepatocellular carcinoma (HCC), It is a Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides, PGCP is a carboxypeptidase that potentially is involved in the hydrolysis of circulating peptides, PGCP is a member of the Peptidase M28 family of proteins, PGCP is found principally in blood plasma, The gene encoding PGCP maps to chromosome 8, Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis, it is suspected that PGCP may be a potential serological marker for HCC, metallopeptidases and aminopeptidases, which also includes PSM (prostate-specific membrane antigen), which is made up of nearly 146 million bases and encodes about 800 genes, In humans, PGCP is a 472 amino acid secreted protein that is primarily detected in blood plasma |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LDP PGCP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PGCP Conjugated |
| Short name: |
Conjugated, PGCP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PGCP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16910 |
| Gene: |
CPQ |
More about : CPQ |
| Long gene name: |
carboxypeptidase Q |
| Synonyms name: |
lysosomal dipeptidase Ser-Met dipeptidase plasma glutamate carboxypeptidase |
| Locus: |
8q22, 1 |
| Discovery year: |
2012-02-17 |
| GenBank acession: |
AF107834 |
| Entrez gene record: |
10404 |
| Pubmed identfication: |
10206990 |
| RefSeq identity: |
NM_016134 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000164690 |