| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SARM1 |
| Specificity: |
This antibody reacts specifically with SARM1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SARM1 |
| Gene ID: |
23098 |
| Swiss Prot: |
Q6SZW1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Can activate neuronal death in response to stress, Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, Involved in innate immune response, Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site, Regulates dendritic arborization through the MAPK4-JNK pathway, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38, Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SARM SAMD2 KIAA0524 |
| Also known as: |
SARM1 Polyclonal Antibody |
| Other name: |
Anti-SARM1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SARM1 |
| Short name: |
Anti-SARM1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SARM1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17074 |
| Gene: |
SARM1 |
More about : SARM1 |
| Long gene name: |
sterile alpha and TIR motif containing 1 |
| Locus: |
17q11, 2 |
| Discovery year: |
2003-05-14 |
| GenBank acession: |
AB011096 |
| Entrez gene record: |
23098 |
| Pubmed identfication: |
9628581 |
| RefSeq identity: |
NM_015077 |
| Classification: |
Sterile alpha motif domain containing TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132499 |