| Long name: |
FITC Conjugated, SARM1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SARM1 |
| Specificity: |
This is a highly specific antibody against SARM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
340-380/724 |
| Source: |
KLH conjugated synthetic peptide derived from human SARM1 |
| Gene ID number: |
23098 |
| Swiss Prot: |
Q6SZW1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can activate neuronal death in response to stress, Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, Involved in innate immune response, Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site, Regulates dendritic arborization through the MAPK4-JNK pathway, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38, Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SARM SAMD2 KIAA0524 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SARM1 Conjugated |
| Short name: |
FITC Conjugated, SARM1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SARM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17074 |
| Gene: |
SARM1 |
More about : SARM1 |
| Long gene name: |
sterile alpha and TIR motif containing 1 |
| Locus: |
17q11, 2 |
| Discovery year: |
2003-05-14 |
| GenBank acession: |
AB011096 |
| Entrez gene record: |
23098 |
| Pubmed identfication: |
9628581 |
| RefSeq identity: |
NM_015077 |
| Classification: |
Sterile alpha motif domain containing TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132499 |