| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HNF1 beta |
| Specificity: |
This antibody reacts specifically with HNF1 beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HNF1 beta |
| Gene ID: |
6928 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, HNF-3 (a, HNF-3a, HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver, HNF-4 (a and g) and HNF-6 compose, HNF-4a and HNF-4g have been shown to be important for early embryo development, HNF-4a is expressed in liver, HNF-6 has been shown to bind to the promoter of HNF-3b, The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, a homoeprotein family designated the hepatocyte nuclear factor family, and HNF-4g is expressed in each of these tissues except liver, b and g), in part, including cytochrome P450 2C13 and a-1 antitrypsin, kidney, pancreas, small intestine, small intestine and thymus, testis and colon, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation, HNF-1 (a and b) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HNF1 LFB1 |
| Also known as: |
HNF1 beta Polyclonal Antibody |
| Other name: |
Anti-HNF1 beta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HNF1 beta |
| Short name: |
Anti-HNF1 beta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HNF1 b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11621 |
| Gene: |
HNF1A |
More about : HNF1A |
| Long gene name: |
HNF1 homeobox A |
| Synonyms gene: |
MODY3 TCF1 |
| Synonyms gene name: |
LF-B1, albumin proximal factor , hepatic, hepatic nuclear factor (HNF1), transcription factor 1 |
| Locus: |
12q24, 31 |
| Discovery year: |
1990-02-12 |
| GenBank acession: |
M57732 |
| Entrez gene record: |
6927 |
| Pubmed identfication: |
1535333 7795649 |
| RefSeq identity: |
NM_000545 |
| Classification: |
HNF class homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000151015 |
| Locus Specific Databases: |
Monogenic Diabetes LRG_522 |