| Long name: |
FITC Conjugated, HNF1 beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HNF1 beta |
| Specificity: |
This is a highly specific antibody against HNF1 beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HNF1 beta |
| Gene ID number: |
6928 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, HNF-3 (a, HNF-3a, HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver, HNF-4 (a and g) and HNF-6 compose, HNF-4a and HNF-4g have been shown to be important for early embryo development, HNF-4a is expressed in liver, HNF-6 has been shown to bind to the promoter of HNF-3b, The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, a homoeprotein family designated the hepatocyte nuclear factor family, and HNF-4g is expressed in each of these tissues except liver, b and g), in part, including cytochrome P450 2C13 and a-1 antitrypsin, kidney, pancreas, small intestine, small intestine and thymus, testis and colon, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation, HNF-1 (a and b) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HNF1 LFB1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HNF1 beta Conjugated |
| Short name: |
FITC Conjugated, HNF1 beta Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HNF1 b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11621 |
| Gene: |
HNF1A |
More about : HNF1A |
| Long gene name: |
HNF1 homeobox A |
| Synonyms gene: |
MODY3 TCF1 |
| Synonyms gene name: |
LF-B1, albumin proximal factor , hepatic, hepatic nuclear factor (HNF1), transcription factor 1 |
| Locus: |
12q24, 31 |
| Discovery year: |
1990-02-12 |
| GenBank acession: |
M57732 |
| Entrez gene record: |
6927 |
| Pubmed identfication: |
1535333 7795649 |
| RefSeq identity: |
NM_000545 |
| Classification: |
HNF class homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000151015 |
| Locus Specific Databases: |
Monogenic Diabetes LRG_522 |