| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RENT1/hUPF1 |
| Specificity: |
This antibody reacts specifically with RENT1/hUPF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RENT1/hUPF1 |
| Gene ID: |
5976 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase, Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential, Rent1, Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, a mammalian ortholog of Upflp, is essential for embryonic viability (1â, it is essential to have the ability to detect and degrade transcripts that lack full coding potential, &euro, &ldquo, 3), In eukaryotes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HUPF1 KIAA0221 NORF1 pNORF1 smg-2 |
| Also known as: |
RENT1/hUPF1 Polyclonal Antibody |
| Other name: |
Anti-RENT1/hUPF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RENT1/hUPF1 |
| Short name: |
Anti-RENT1/hUPF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RENT1/hUPF1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9962 |
| Gene: |
UPF1 |
More about : UPF1 |
| Long gene name: |
RNA helicase and ATPase , UPF1 |
| Synonyms gene: |
RENT1 |
| Synonyms gene name: |
regulator of nonsense transcripts 1 UPF1 regulator of nonsense transcripts homolog (yeast) |
| Synonyms name: |
UP Frameshift 1 smg-2 homolog, elegans) , nonsense mediated mRNA decay factor (C |
| Locus: |
19p13, 11 |
| Discovery year: |
1997-02-11 |
| GenBank acession: |
AF074016 |
| Entrez gene record: |
5976 |
| Pubmed identfication: |
8855285 9064659 |
| RefSeq identity: |
NM_002911 |
| Classification: |
UPF1 like RNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000183025 |