| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
OLIG1 |
| Specificity: |
This antibody reacts specifically with OLIG1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human OLIG1 |
| Gene ID: |
116448 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
OLIG proteins are candidates for molecular markers of human glial brain tumors, OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas, OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis, OLIG1 and OLIG2 interact with the Nkx-2, OLIG2 is more widely expressed in embryonic brain than OLIG1, Therefore, These interactions between OLIG proteins and Nkx-2, which are the most common primary malignancies of the human brain, which differ in tissue expression, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube, while OLIG3 is primarily expressed in non-neural tissues, 2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development, 2 homeodomain protein, The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BHLHB6 bHLHe21 |
| Also known as: |
OLIG1 Polyclonal Antibody |
| Other name: |
Anti-OLIG1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
OLIG1 |
| Short name: |
Anti-OLIG1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-OLIG1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16983 |
| Gene: |
OLIG1 |
More about : OLIG1 |
| Long gene name: |
oligodendrocyte transcription factor 1 |
| Synonyms name: |
6 , class B, helix-loop-helix protein, oligodendrocyte-specific bHLH transcription factor 1 oligodendrocyte lineage transcription factor 1 basic domain |
| Locus: |
21q22, 11 |
| Discovery year: |
2001-12-04 |
| GenBank acession: |
AP000109 |
| Entrez gene record: |
116448 |
| Pubmed identfication: |
11526205 |
| RefSeq identity: |
NM_138983 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000065064 |