| Long name: |
OLIG1 Primary Polyclonal Antibody |
| Also known as: |
OLIG1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
OLIG1 |
| Specificity: |
This is a highly specific antibody against OLIG1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OLIG1 |
| Gene ID number: |
116448 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
OLIG proteins are candidates for molecular markers of human glial brain tumors, OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas, OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis, OLIG1 and OLIG2 interact with the Nkx-2, OLIG2 is more widely expressed in embryonic brain than OLIG1, Therefore, These interactions between OLIG proteins and Nkx-2, which are the most common primary malignancies of the human brain, which differ in tissue expression, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube, while OLIG3 is primarily expressed in non-neural tissues, 2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development, 2 homeodomain protein, The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BHLH B6, BHLHB 6, BHLHB6, Basic domain helix loop helix protein class B 6, Basic domain helix loop helix protein class B6, Class B basic helix-loop-helix protein 6, Class E basic helix-loop-helix protein 21, OLIG1_HUMAN, Olig 1, Olig1, Oligo1, Oligodendrocyte lineage transcription factor 1, Oligodendrocyte specic bHLH transcription factor 1, Oligodendrocyte transcription factor 1, bHLHe21, Oligo 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OLIG1 |
| Short name: |
OLIG1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
OLIG1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16983 |
| Gene: |
OLIG1 |
More about : OLIG1 |
| Long gene name: |
oligodendrocyte transcription factor 1 |
| Synonyms: |
BHLHB6 bHLHe21 |
| Synonyms name: |
6 , class B, helix-loop-helix protein, oligodendrocyte-specific bHLH transcription factor 1 oligodendrocyte lineage transcription factor 1 basic domain |
| Locus: |
21q22, 11 |
| Discovery year: |
2001-12-04 |
| GenBank acession: |
AP000109 |
| Entrez gene record: |
116448 |
| Pubmed identfication: |
11526205 |
| RefSeq identity: |
NM_138983 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000065064 |