| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ELL |
| Specificity: |
This antibody reacts specifically with ELL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ELL |
| Gene ID: |
8178 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ELL (11-19 lysine-rich leukemia protein), ELL is abundantly expressed in peripheral blood leukocytes, Elongation is thought to be a critical stage for the regulation of gene expression, It is also thought to regulate cellular proliferation, MLL (myeloid/lymphoid leukemia, The gene encoding human ELL, This is a multistep process, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development, also designated MEN, brain, called the transcription cycle, clearance, elongation and termination, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II, heart, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia, kidney, liver and ovary, lung, placenta and testis, promoter, skeletal muscle, that includes five stages: preinitiation, thymus, which maps to chromosome 19p13, with lower expression in spleen, 1, Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Men ELL1 PPP1R68 |
| Also known as: |
ELL Polyclonal Antibody |
| Other name: |
Anti-ELL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ELL |
| Short name: |
Anti-ELL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ELL (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23114 |
| Gene: |
ELL |
More about : ELL |
| Long gene name: |
elongation factor for RNA polymerase II |
| Synonyms gene: |
C19orf17 |
| Synonyms gene name: |
chromosome 19 open reading frame 17 elongation factor RNA polymerase II |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 68 eleven-nineteen lysine-rich leukemia gene |
| Locus: |
19p13, 11 |
| Discovery year: |
2003-09-17 |
| GenBank acession: |
U16282 |
| Entrez gene record: |
8178 |
| Pubmed identfication: |
7991593 8596958 |
| RefSeq identity: |
NM_006532 |
| Classification: |
Protein phosphatase 1 regulatory subunits Super elongation complex |
| Havana BLAST/BLAT: |
OTTHUMG00000183364 |