| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FBXL3 |
| Specificity: |
This antibody reacts specifically with FBXL3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FBXL3 |
| Gene ID: |
26224 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation, The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2, Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBL3 FBL3A |
| Also known as: |
FBXL3 Polyclonal Antibody |
| Other name: |
Anti-FBXL3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FBXL3 |
| Short name: |
Anti-FBXL3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FBXL3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13599 |
| Gene: |
FBXL3 |
More about : FBXL3 |
| Long gene name: |
F-box and leucine rich repeat protein 3 |
| Synonyms gene: |
FBXL3A |
| Synonyms gene name: |
F-box and leucine-rich repeat protein 3A |
| Locus: |
13q22, 3 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
AF129532 |
| Entrez gene record: |
26224 |
| Pubmed identfication: |
10531035 10828603 |
| Classification: |
F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000017099 |