| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
beta COP |
| Specificity: |
This antibody reacts specifically with beta COP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human beta COP |
| Gene ID: |
1315 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Beta COP is a member of a set of protein which are believed to associate with the non-clathrin coated vesicles, Clathrin-coated vesicles carry proteins to endocytic organelles and secretory granules, Golgi-derived non-clathrin-coated vesicles are believed to act as bulk carriers, Membrane traffic from the endoplasmic reticulum (ER) to the Golgi complex and from the Golgi complex to the different final cellular destinations is believed to be mediated by carrier vesicles, Two populations of coated vesicles mediate biosynthetic membrane traffic between the different membrane-bound compartments, whereas clathrin-coated vesicles carry a selective cargo of membrane proteins, whilst non-clathrin-coated vesicles are involved in intra-Golgi transport and transport from the ER to the Golgi complex, The Golgi complex is a key organelle where processing and sorting of newly synthesized proteins occurs |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
COP1 COP PSEUDO-ICE |
| Also known as: |
beta COP Polyclonal Antibody |
| Other name: |
Anti-beta COP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
beta COP |
| Short name: |
Anti-beta COP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-b COP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
33701 |
| Gene: |
CARD16 |
More about : CARD16 |
| Long gene name: |
caspase recruitment domain family member 16 |
| Synonyms gene name: |
caspase recruitment domain family, member 16 |
| Locus: |
11q22, 3 |
| Discovery year: |
2008-09-15 |
| Entrez gene record: |
114769 |
| Pubmed identfication: |
11432859 11536016 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166157 |