| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
COPA/alpha COP I |
| Specificity: |
This antibody reacts specifically with COPA/alpha COP I |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human COPA/alpha COP I |
| Gene ID: |
1314 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
COPD and COPZ subunits (also known as b-, COPG, COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport, COPP and e-COP, In the gut, Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles, The cytosolic precursor of the COPI coat, The first consists of the COPB, The second consists of the COPA, Xenin interacts with the neurotensin receptor, Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid, b'-COP and COPE subunits (also known as a-COP, d- and z-COP, g-, is composed of two subcomplexes, respectively), respectively), the heptameric coatomer complex, which are distantly homologous to AP Clathrin adaptor subunits, COPA (alpha-coat protein) is processed to produce Xenin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HEP-COP |
| Also known as: |
COPA/alpha COP I Polyclonal Antibody |
| Other name: |
Anti-COPA/alpha COP I Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
COPA/alpha COP I |
| Short name: |
Anti-COPA/alpha COP I (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-COPA/a COP I (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2230 |
| Gene: |
COPA |
More about : COPA |
| Long gene name: |
coatomer protein complex subunit alpha |
| Synonyms gene name: |
coatomer protein complex, subunit alpha |
| Synonyms name: |
proxenin xenin |
| Locus: |
1q23, 2 |
| Discovery year: |
1996-11-15 |
| GenBank acession: |
U24105 |
| Entrez gene record: |
1314 |
| Pubmed identfication: |
8647451 |
| RefSeq identity: |
NM_004371 |
| Classification: |
Endogenous ligands WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000033111 |