| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAGED1 |
| Specificity: |
This antibody reacts specifically with MAGED1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MAGED1 |
| Gene ID: |
9500 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds p75NTR and antagonizes its association with TrkA, Enhances p53 phosphorylation and accumulation, May act as a regulator of the function of DLX family members, May regulate p53 transcriptional activity and inhibit cell proliferation, and facilitates p75NTR-mediated apoptosis, inhibits cell cycle progression, Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NRAGE DLXIN-1 |
| Also known as: |
MAGED1 Polyclonal Antibody |
| Other name: |
Anti-MAGED1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAGED1 |
| Short name: |
Anti-MAGED1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
1 (polyclonal), ALEXA Fluor 594, antibody to-melanoma antigen family D |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
1, BT, DLXIN-1 and NRAGE, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0042752 and regulation of circadian rhythm and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, MAGED1 and IDBG-67550 and ENSG00000179222 and 9500, Maged1 and IDBG-160245 and ENSMUSG00000025151 and 94275, nuclei, protein binding, this GO :0000785 and chromatin and cellular component this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0003713 : transcription coactivator activity, this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 62984 and IDBG-637328 and ENSBTAG00000008733 and 512562, melanoma antigen family D |
| Identity: |
6813 |
| Gene: |
MAGED1 |
More about : MAGED1 |
| Long gene name: |
MAGE family member D1 |
| Synonyms gene name: |
melanoma antigen family D1 |
| Locus: |
Xp11, 22 |
| Discovery year: |
1999-04-14 |
| GenBank acession: |
AF124440 |
| Entrez gene record: |
9500 |
| Pubmed identfication: |
10409427 |
| RefSeq identity: |
NM_001005332 |
| Classification: |
MAGE family |
| Havana BLAST/BLAT: |
OTTHUMG00000021540 |
| Locus Specific Databases: |
Mental Retardation database |