| Long name: |
127) Monoclonal Antibody, 157, MAGED1 (1305CT862 |
| Also known as: |
127) Monoclonal Antibody, 157, MAGED1 (1305CT862 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MAGED1 |
| Specificity: |
This is a highly specific antibody against MAGED1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
127, 1305CT862, 157 |
| Source: |
This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1 |
| Gene ID number: |
9500 |
| Swiss Prot: |
Q9Y5V3 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Inhibits cell cycle progression, May act as RORA co-regulator, May act as a regulator of the function of DLX family members, May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, Plays a role in the circadian rythm regulation, Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex, and facilitates NGFR-mediated apoptosis, induced, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, or NR1D1, repressed, Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells |
| Purification method: |
This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DLXIN-1, MAGE tumor antigen CCF, MAGE-D1 antigen, MAGED1, Melanoma-associated antigen D1, Neurotrophin receptor-interacting MAGE homolog, PP2250, PRO2292, NRAGE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
127) Monoclonal, 157, MAGED1 (1305CT862 |
| Short name: |
127) Monoclonal Antibody, 157, MAGED1 (1305CT862 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
1 (1305CT862, 127) monoclonal (Antibody to), 157, melanoma antigen family D |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
1, BT, DLXIN-1 and NRAGE, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0042752 and regulation of circadian rhythm and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, MAGED1 and IDBG-67550 and ENSG00000179222 and 9500, Maged1 and IDBG-160245 and ENSMUSG00000025151 and 94275, nuclei, protein binding, this GO :0000785 and chromatin and cellular component this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0003713 : transcription coactivator activity, this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 62984 and IDBG-637328 and ENSBTAG00000008733 and 512562, melanoma antigen family D |
| Identity: |
6813 |
| Gene: |
MAGED1 |
More about : MAGED1 |
| Long gene name: |
MAGE family member D1 |
| Synonyms gene name: |
melanoma antigen family D1 |
| Synonyms: |
NRAGE DLXIN-1 |
| Locus: |
Xp11, 22 |
| Discovery year: |
1999-04-14 |
| GenBank acession: |
AF124440 |
| Entrez gene record: |
9500 |
| Pubmed identfication: |
10409427 |
| RefSeq identity: |
NM_001005332 |
| Classification: |
MAGE family |
| Havana BLAST/BLAT: |
OTTHUMG00000021540 |
| Locus Specific Databases: |
Mental Retardation database |