| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
STK17A |
| Specificity: |
This antibody reacts specifically with STK17A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DRAK1/STK17A |
| Gene ID: |
9263 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DRAK1 messenger RNA appears to be ubiquitously expressed in human tissues, DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain, It has been shown in vitro that DRAK1 is capable of autophosphorylation and of phosphorylating the myosin light chain as an exogenous substrate, Overexpression of DRAK1 induces apoptosis, The full-length cDNA encodes a deduced 414-amino acid protein with a molecular mass of 46, and that the noncatalytic C terminus is crucial for full kinase activity, which mediate apoptosis through their catalytic activities, 56 kD, DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) is a novel member of the ser/thr protein kinase family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DRAK1 |
| Also known as: |
STK17A Polyclonal Antibody |
| Other name: |
Anti-STK17A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
STK17A |
| Short name: |
Anti-STK17A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-serine/threonine kinase 17a (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, DRAK1, STK17A and IDBG-13708 and ENSG00000164543 and 9263, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :2000271 and positive regulation of fibroblast apoptotic process and biological process this GO :2000377 and regulation of reactive oxygen species metabolic process and biological process, 52411 and IDBG-634435 and ENSBTAG00000008143 and 513665, serine/threonine kinase 17a |
| Identity: |
11395 |
| Gene: |
STK17A |
More about : STK17A |
| Long gene name: |
serine/threonine kinase 17a |
| Synonyms gene name: |
serine/threonine kinase 17a (apoptosis-inducing) |
| Synonyms name: |
death-associated protein kinase-related 1 |
| Locus: |
7p13 |
| Discovery year: |
1999-05-21 |
| GenBank acession: |
AB011420 |
| Entrez gene record: |
9263 |
| Pubmed identfication: |
9786912 |
| RefSeq identity: |
NM_004760 |
| Classification: |
Death associated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000022825 |