| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PRMT4 |
| Specificity: |
This antibody reacts specifically with PRMT4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PRMT4 |
| Gene ID: |
10498 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
At least two transcript variants encoding the same protein have been found for this gene (from EntrezGene), It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence, It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer, P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence, The microsatellite is polymorphic, This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death, which are enzymes involved in cellular responses to oxidative stresses and irradiation, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53, The protein encoded by this gene is similar to oxidoreductases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRMT4 |
| Also known as: |
PRMT4 Polyclonal Antibody |
| Other name: |
Anti-PRMT4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PRMT4 |
| Short name: |
Anti-PRMT4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PRMT4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23393 |
| Gene: |
CARM1 |
More about : CARM1 |
| Long gene name: |
coactivator associated arginine methyltransferase 1 |
| Locus: |
19p13, 2 |
| Discovery year: |
2003-11-14 |
| GenBank acession: |
AF055027 |
| Entrez gene record: |
10498 |
| Pubmed identfication: |
10381882 11724789 |
| RefSeq identity: |
NM_199141 |
| Classification: |
Protein arginine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000180699 |