| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SERINC3 |
| Specificity: |
This antibody reacts specifically with SERINC3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SERINC3 |
| Gene ID: |
10955 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also found on the membranes of the Golgi apparatus within cells, Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type, It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis, TDE1 is highly expressed in neuronal populations but is also found in thymus, The mechanism through which TDE1 protects cells is poorly understood, This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue, but may involve aberrant methylation of TDE1 complexes, is a multi-pass membrane protein also known as serine incorporator 3, kidney, liver and testis, tumor differentially expressed protein 1, TDE1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DIFF33 TDE SBBI99 TMS-1 AIGP1 |
| Also known as: |
SERINC3 Polyclonal Antibody |
| Other name: |
Anti-SERINC3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SERINC3 |
| Short name: |
Anti-SERINC3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-serine incorporator 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AIGP1 and DIFF33 and SBBI99 and TDE and TDE1 and TMS-1, Plasma membranes, SERINC3 and IDBG-642804 and ENSBTAG00000002187 and 511861, SERINC3 and IDBG-76679 and ENSG00000132824 and 10955, Serinc3 and IDBG-211926 and ENSMUSG00000017707 and 26943, this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :1902237 and positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, serine incorporator 3 |
| Identity: |
11699 |
| Gene: |
SERINC3 |
More about : SERINC3 |
| Long gene name: |
serine incorporator 3 |
| Synonyms gene: |
TDE1 |
| Synonyms gene name: |
tumor differentially expressed 1 |
| Locus: |
20q13, 12 |
| Discovery year: |
1999-12-07 |
| GenBank acession: |
U49188 |
| Entrez gene record: |
10955 |
| Pubmed identfication: |
10559794 |
| RefSeq identity: |
NM_006811 |
| Havana BLAST/BLAT: |
OTTHUMG00000033087 |