| Long name: |
FITC Conjugated, SERINC3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SERINC3 |
| Specificity: |
This is a highly specific antibody against SERINC3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human SERINC3 |
| Gene ID number: |
10955 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also found on the membranes of the Golgi apparatus within cells, Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type, It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis, TDE1 is highly expressed in neuronal populations but is also found in thymus, The mechanism through which TDE1 protects cells is poorly understood, This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue, but may involve aberrant methylation of TDE1 complexes, is a multi-pass membrane protein also known as serine incorporator 3, kidney, liver and testis, tumor differentially expressed protein 1, TDE1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DIFF33 TDE SBBI99 TMS-1 AIGP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SERINC3 Conjugated |
| Short name: |
FITC Conjugated, SERINC3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, serine incorporator 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AIGP1 and DIFF33 and SBBI99 and TDE and TDE1 and TMS-1, Plasma membranes, SERINC3 and IDBG-642804 and ENSBTAG00000002187 and 511861, SERINC3 and IDBG-76679 and ENSG00000132824 and 10955, Serinc3 and IDBG-211926 and ENSMUSG00000017707 and 26943, this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :1902237 and positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, serine incorporator 3 |
| Identity: |
11699 |
| Gene: |
SERINC3 |
More about : SERINC3 |
| Long gene name: |
serine incorporator 3 |
| Synonyms gene: |
TDE1 |
| Synonyms gene name: |
tumor differentially expressed 1 |
| Locus: |
20q13, 12 |
| Discovery year: |
1999-12-07 |
| GenBank acession: |
U49188 |
| Entrez gene record: |
10955 |
| Pubmed identfication: |
10559794 |
| RefSeq identity: |
NM_006811 |
| Havana BLAST/BLAT: |
OTTHUMG00000033087 |