| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TAB1 |
| Specificity: |
This antibody reacts specifically with TAB3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TAB3 |
| Gene ID: |
257397 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants have been described, Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor, The encoded protein, The human genome contains a related pseudogene, and the similar and functionally redundant protein MAP3K7IP2/TAB2, but their biological validity has not been determined, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1, The product of this gene functions in the NF-kappaB signal transduction pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
TAB3 Polyclonal Antibody |
| Other name: |
Anti-TAB3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TAB3 |
| Short name: |
Anti-TAB3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TAB3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30681 |
| Gene: |
TAB3 |
More about : TAB3 |
| Long gene name: |
TGF-beta activated kinase 1 and MAP3K7 binding protein 3 |
| Synonyms gene: |
MAP3K7IP3 |
| Synonyms gene name: |
mitogen-activated protein kinase kinase kinase 7 interacting protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
| Synonyms name: |
TAK1 binding protein 3 |
| Locus: |
Xp21, 2 |
| Discovery year: |
2006-06-26 |
| GenBank acession: |
AY331591 |
| Entrez gene record: |
257397 |
| Pubmed identfication: |
14633987 14670075 |
| RefSeq identity: |
NM_152787 |
| Classification: |
Zinc fingers RANBP2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000021329 |
| Locus Specific Databases: |
Mental Retardation database |