| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TAB3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 4-8ug/ml |
| Notes: |
antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This TAB3 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
257397 |
| Purity: |
This antibody was purified by Protein A method |
| Description: |
IL-1 and TNF are cytokines involved in the inflammation process, Phosphorylation leads to IkB degradation, TAB3 functions as an adapter, This kinase complex phosphorylates IkB, a TAB2-like protein, activating NF-kB, binds to DNA response elements and can begin multiple signaling cascades, initiating signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (MAPKs), is a mediator of TAK1 activation in IL-1 and TNF signaling, linking TAK1 and TRAF6 or TRAF2, which keeps NF-kB inactive and sequestered in the cytoplasm, which translocates to the nucleus, TAB3 |
| Immunogen: |
A recombinant protein fragment from the N-terminal region of human TAB3 was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TAB3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TAB3 |
| Short name: |
TAB3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TAB3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30681 |
| Gene: |
TAB3 |
More about : TAB3 |
| Long gene name: |
TGF-beta activated kinase 1 and MAP3K7 binding protein 3 |
| Synonyms gene: |
MAP3K7IP3 |
| Synonyms gene name: |
mitogen-activated protein kinase kinase kinase 7 interacting protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
| Synonyms name: |
TAK1 binding protein 3 |
| Locus: |
Xp21, 2 |
| Discovery year: |
2006-06-26 |
| GenBank acession: |
AY331591 |
| Entrez gene record: |
257397 |
| Pubmed identfication: |
14633987 14670075 |
| RefSeq identity: |
NM_152787 |
| Classification: |
Zinc fingers RANBP2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000021329 |
| Locus Specific Databases: |
Mental Retardation database |