Anti-NMDAR2B (Tyr1252) (Polyclonal), ALEXA Fluor 594

Catalog number:	GENTAUR-58be636b12b9c Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Anti-NMDAR2B (Tyr1252) (Polyclonal), ALEXA Fluor 594
Quantity:	100ul
Related search:	tyr polyclonal antibody gene receptor nmda ionotropic dapk

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	NMDAR2B Tyr1252
Specificity:	NMDAR2B (Tyr1252), This antibody may cross react with NMDAR2A (Tyr 1246) due to 75% sequence similarity
Modification:	Phosphorylation
Modification site:	Tyr1252
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Subcellular locations:	Cytoplasm
Antigen Source:	KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252
Gene ID:	2904
Swiss Prot:	Q13224
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	GluN2B
Also known as:	NMDAR2B (Tyr1252) Polyclonal Antibody
Other name:	Anti-NMDAR2B (Tyr1252) Polyclonal
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Group:	Polyclonals and antibodies
About:	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target:	NMDAR2B (Tyr1252)
Short name:	Anti-NMDAR2B (Tyr1252) (Polyclonal) Fluor 594
Technique:	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-NMDAR2B (Tyr1252) (polyclonal)
Alternative technique:	polyclonals
Identity:	4586
Gene:	GRIN2B | More about : GRIN2B
Long gene name:	glutamate ionotropic receptor NMDA type subunit 2B
Synonyms gene:	NMDAR2B
Synonyms gene name:	N-methyl D-aspartate 2B , glutamate receptor, ionotropic
Locus:	12p13, 1
Discovery year:	1992-09-18
Entrez gene record:	2904
Pubmed identfication:	1350383
Classification:	Glutamate ionotropic receptor NMDA type subunits
Havana BLAST/BLAT:	OTTHUMG00000137373

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