| Long name: |
ALEXA FLUOR 647 Conjugated, NMDAR2B (Tyr1252) Polyclonal Antibody |
| Also known as: |
Anti-NMDAR2B Tyr1252 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NMDAR2B Tyr1252 |
| Specificity: |
This is a highly specific antibody against NMDAR2B Tyr1252 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr1252 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1230-1280/1484 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252 |
| Gene ID Number: |
2904 |
| Swiss Prot: |
Q13224 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In concert with DAPK1 at extrasynaptic sites, Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, Mediated by glycine, acts as a central mediator for stroke damage, resulting in an irreversible neuronal death (By similarity), NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
GluN2B |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the NMDAR2B (Tyr1252) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
NMDAR2B (Tyr1252) |
| Short name: |
NMDAR2B (Tyr1252) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, NMDAR2B (Tyr1252) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4586 |
| Gene: |
GRIN2B |
More about : GRIN2B |
| Long gene name: |
glutamate ionotropic receptor NMDA type subunit 2B |
| Synonyms gene: |
NMDAR2B |
| Synonyms gene name: |
N-methyl D-aspartate 2B , glutamate receptor, ionotropic |
| Locus: |
12p13, 1 |
| Discovery year: |
1992-09-18 |
| Entrez gene record: |
2904 |
| Pubmed identfication: |
1350383 |
| Classification: |
Glutamate ionotropic receptor NMDA type subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000137373 |