| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PLCZ1 |
| Specificity: |
This antibody reacts specifically with PLCZ1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PLCZ1 |
| Gene ID: |
89869 |
| Swiss Prot: |
Q86YW0 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In vitro, Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion, May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage, hydrolyzes PtdIns(4, including CFTR trafficking and function, 4, 5)P2 in a Ca(2+)-dependent manner, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes, The production of the second messenger molecules diacylglycerol (DAG) and inositol 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NYD-SP27 PLCzeta |
| Also known as: |
PLCZ1 Polyclonal Antibody |
| Other name: |
Anti-PLCZ1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PLCZ1 |
| Short name: |
Anti-PLCZ1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PLCZ1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19218 |
| Gene: |
PLCZ1 |
More about : PLCZ1 |
| Long gene name: |
phospholipase C zeta 1 |
| Synonyms gene name: |
phospholipase C, zeta 1 |
| Locus: |
12p12, 3 |
| Discovery year: |
2002-09-13 |
| GenBank acession: |
AY035866 |
| Entrez gene record: |
89869 |
| Pubmed identfication: |
12117804 |
| RefSeq identity: |
NM_033123 |
| Classification: |
Phospholipases C2 domain containing phospholipases EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168937 |